Oregon (15-2, 4-0) found a way to win and that is all that matters when you play on the road in college basketball.
The Ducks are off to their best start in league play since 1973-74.
USC (7-11, 2-3) had four chances to take the lead or tie the game during their final possession but couldn't get a shot to fall.
Senior Arsalan Kazemi grabbed his game-high 11th rebound with 1.9 seconds left and was sent to the free throw line. Kazemi missed the front end of a 1-and-1 and time expired for Oregon's 76-74 victory.
Senior E.J. Singler was one of five players in double figures scoring and led Oregon with 14 points, seven assists, and seven rebounds and just one turnover.
Freshman Daymean Dotson added 14 points for the Ducks. Carlos Emory added 12 points and Dominic Artis and Johnathan Loyd scored 10 each.
Oregon was sluggish all night and never looked to be fully into the game. USC was able to dictate the style of play and make it an ugly basketball game.
The Ducks who started out scorching hot finished the night shooting just 42.9-percent while the Trojans were just a hair better shooting 45.3-percent. Both teams also struggled from three and from the line.
Yet this was still a huge win for Oregon in multiple fronts.
The Ducks are now 4-0 in league play and have their best start in conference play since 1973-74.
SC's 74 points is USC's third highest scoring output of the season and yet Oregon was able to grind out 76 points - the second most points allowed by USC all year.
The Ducks also once again dominated the paint. The Ducks beat USC on the boards 37-26 and also won the offensive rebound advantage 12-7. Oregon also had 16 assists on 27 made baskets which is a good radio.
Most importantly however Oregon's turnovers have continued to drop significantly. Thursday night Oregon only committed eight turnovers.
Oregon went into the half leading 35-31 after the Trojans fouled Emory on a buzzer-beating three-point attempt. Emory made two of three.
USC's J.T. Terrell led all players with 22 points.